原创 廖博士 审校 黄向东 今天
APRIL 16, 2020 -- Exposing contaminated N95 respirators to vaporized hydrogen peroxide (VHP) or ultraviolet (UV) light appears to eliminate the SARS-CoV-2 virus from the material and preserve the integrity of the masks' fit for up to three uses, a National Institutes of Health (NIH) study shows.
2020年4月16日——美国国家卫生研究院（NIH）的一项研究显示，将受污染的N95口罩暴露在蒸发的过氧化氢（VHP）或紫外线（UV）下，可以消除材料中的SARS-CoV-2病毒，并保持口罩的完整性，可以重复使用三次。
Dry heat (70° C) was also found to eliminate the virus on masks but was effective for two uses instead of three.
干热（70°C）也能消除口罩上的病毒，但只能重复两次。
Fischer and colleagues compared four methods for decontaminating the masks, which are designed for one-time use: UV radiation (260 – 285 nm); 70° C dry heat; 70% ethanol spray; and VHP.
菲舍尔和同事比较了四种一次性使用口罩的消毒方法：紫外线（260-285nm）；70°C干热；70%乙醇喷雾；VHP。
All four methods eliminated detectable SARS-CoV-2 virus from the fabric test samples, though the time needed for decontamination varied. VHP was the quickest, requiring 10 minutes. Dry heat and UV light each required approximately 60 minutes. Ethanol required an intermediate amount of time.
所有四种方法都从织物测试样品中消除了可检测到的SARS-CoV-2病毒，尽管消毒所需的时间不同。VHP是最快的，需要10分钟。干热和紫外光各需要大约60分钟。乙醇需要30分钟。
To test durability over three uses, the researchers treated intact, clean masks with the same decontamination method and assessed function via quantitative fit testing.
为了测试三种用途的耐用性，研究人员用相同的消毒方法处理了完整、干净的口罩，并测试评估了其功能。
The researchers found that masks that had been decontaminated with ethanol spray did not function effectively after decontamination.
研究人员发现，用乙醇喷雾去污的口罩在消毒并不能有效发挥作用。
By contrast, masks decontaminated with UV and VHP could be used up to three times and function properly. Masks decontaminated with dry heat could be used two times before function declined.
相比之下，用紫外线和VPH消毒的口罩可以使用三次，并且功能正常。干热消毒口罩可使用两次。
The results will reassure clinicians, many of whom are already using these decontamination methods
研究结果将使已经在使用这些去污消毒的临床医生放心.
文章出处
Assessment of N95 respirator decontamination and re-use for SARS-CoV-2
Robert Fischer, doi: https://doi.org/10.1101/2020.04.11.20062018
