2型糖尿病的終極療法,竟然隱藏在維生素D的背後!

[8] Theodoulou, N.H., Bamborough, P., Bannister, A.J., Becher, I., Bit, R.A., Che,K.H., Chung, C.W., Dittmann, A., Drewes, G., Drewry, D.H., et al. (2016). Discovery of I-BRD9, a selective cell active chemical probe for bromodomain containing protein 9 inhibition. J. Med. Chem. 59, 1425–1439.

[9] Chan, J.Y., Luzuriaga, J., Bensellam, M., Biden, T.J., and Laybutt, D.R. (2013).Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in b-cell gene expression and progression to diabetes. Diabetes 62, 1557–1568.

[10] Garris, D.R., and Garris, B.L. (2004). Cytochemical analysis of pancreatic islet hypercytolipidemia following diabetes (db/db) and obese (ob/ob) mutation expression: influence of genomic background. Pathobiology 71, 231–240.

[11]https://www.sciencedaily.com/releases/2018/05/180510115102.htm


分享到:


相關文章: