Yes, you can!
1 used to indicate the place where someone or something is 表示发生地点（固定搭配）
They're staying at a hotel.
He was sitting at the table.
The kitchen is at the back of the house.
The party will be at Bella’s house.
We met at a party.
There were 200 people at the wedding.
They live at opposite ends of town.
His father is at home.
He’s working late at the office.
She met us at the door.
2 used to indicate the person or thing toward which an action, motion, or feeling is directed or aimed 表示作用对象
She looked directly at me.
She pointed her gun at the target.
He’s angry at his brother.
His anger is directed at his brother.
She shouted abuse at me.
They laughed at him.
She grabbed at my arm.
He poked at his food.
3 used to indicate something that is being tried or attempted 表示尝试
I made an attempt at persuading him to go.
I took a shot at doing it myself.
4 because of or in reaction to (something) 表示原因
She's furious at how slowly the investigation is proceeding.
They laughed at my joke.
I was greatly surprised at/by the result.
She visited the museum at my suggestion.
You can act at your own discretion.
5 used to indicate an activity 表示某方面如何
I’m bad at chess.
She’s doing very well at her studies.
6 used to indicate a situation or condition 表示某种情况或条件
He's very serious when he's at work.
Children are at play.
I’m not at liberty to discuss that.
She’s now at rest.
The two nations that are at war will cease fire soon.
People who are at risk have to be isolated.
He is now at peace.
7 used to indicate a temperature, speed, price, etc 表示具体温度、速度、价格
The temperature is at 24 degrees.
He was driving at almost 80 miles an hour.
They sell at a dollar a dozen.
8 used to indicate an age or time 表示年龄或时间
He plans to retire at 65.
He called at nine o’clock.
I was present at my son’s birth.
He left at dawn/noon/sunset/night.
9 used to indicate the method by which something is done 表示方法
The property was sold at auction.
10 used in phrases like at (its) best, at (its) worst, etc., to indicate a possible result or condition that is considered best, worst, etc. 用于at (its) best, at (its) worst
The company will make a small profit at best this year.
We might be 5 or 10 minutes late at our worst.
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