01.31 科学家制作了变色绷带,旨在检测细菌感染

科学家制作了变色绷带,旨在检测细菌感染

Scientists have developed a new type of smart bandage that can signal the type of bacterial infection it's protecting, just like a traffic light, as well as release the right type of drugs on demand.

科学家们已经开发出一种新型的智能绷带,可以像交通灯一样发出信号,指示它所保护的细菌感染的类型,并根据需要释放正确类型的药物。

The researchers behind the design hope it could help to fight back against antibiotic resistance, as well as heal wounds more quickly.

这项设计背后的研究人员希望它可以帮助对抗抗生素耐药性,以及更快地愈合伤口。

The traffic light system works just like you'd expect: Green means no bacteria or a low concentration of bacteria, yellow means drug-sensitive (DS) bacteria responsive to standard antibiotics (and triggers antibiotic release), and red means drug-resistant (DR) bacteria that need extra help to be wiped out.

交通灯系统就像你预期的那样工作:绿色表示没有细菌或低浓度的细菌,黄色表示对标准抗生素有反应的药物敏感(DS)细菌(并触发抗生素释放),红色表示需要额外帮助才能消灭的耐药(DR)细菌。

The stronger the colour, the higher the concentration of bacteria.

颜色越浓,细菌的浓度就越高。

In testing the bandage on mice, the research team was able to successfully treat both DS and DR E. coli infections using the new method.

在老鼠身上测试绷带时,研究小组能够使用新方法成功治疗DS和DR大肠杆菌感染。

If drug resistance is detected, an intense beam of light can be used to activate the release of a highly reactive species of oxygen to weaken the bacteria, making them more susceptible to the antibiotic in the material.

如果检测到耐药性,一束强烈的光束可以用来激活释放一种高活性的氧气来削弱细菌,使它们更容易受到材料中的抗生素的影响。

Bandage colours for drug-sensitive (DS) and drug-resistant (DR) bacteria.

用于药物敏感(DS)和耐药(DR)细菌的绷带颜色。

(ACS Central Science 2020)

(ACS Central Science 2020)


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